The CNRPH is a reference institution that provides care for people with disabilities in Cameroon. It is located in the sixth district of the city of Yaoundé. We observed that many people with motor and hearing impairments attend this social institution to receive care. Thanks to its long-standing experience and technical facilities, the Center provides holistic care to all its patients. In 2024, we conducted a study on the monitoring and support provided to people with these two types of disabilities. The theory of social assistance was adopted for this research. We therefore used direct observation, semi-structured interviews and life stories as data collection methods. The effectiveness of care for people with disabilities is reflected in their autonomy, which is a major indicator of the effectiveness of the work carried out by the Centre’s specialists. After receiving multidisciplinary care at the CNRPH, people with motor and hearing impairments can manage their own needs more easily and integrate into society. Through snowball sampling, we collected life stories from people with disabilities concerning the effectiveness of care at the CNRPH.